Reform of Cinnamol Dehydrogenase Technology


Reform of Cinnamol Dehydrogenase Technology
Cinnamyl alcohol dehydrogenase (CAD), as a key enzyme of plant secondary metabolism, especially lignin synthesis, is closely related to plant growth and development and resistance to pathogen invasion. Lignin is one of the components of plant cell wall, which has the function of connecting cells. It can strengthen cell wall and adhesive fiber in plant tissue. Its composition and properties are complex, and it has very strong activity. Substances with relatively high molecular weight that are difficult to hydrolyze under the action of acid mainly exist in the cells of lignified plants and strengthen plant tissues. In addition, lignin also has anti-tumor effect, liver protection and antioxidant effect, antiviral effect, smooth muscle spasmolysis effect, cAMP phosphodiesterase inhibition activity, immune enhancement, and promotion of protein and glycogen synthesis.
As the key enzyme for lignin synthesis, RT-PCR and RACE methods are currently used to isolate a gene of CAD gene family from Xiaoshun bamboo shoots, and cloning technology is used to produce CAD, but the cost is so high that the price of downstream products is also rising, which brings great difficulties to the application of products.
However, the latest research shows that using dehydrogenase to catalyze the reduction of cinnamyl alcohol and its derivatives in NADPH can effectively synthesize CAD. This research achievement is a major breakthrough in solving the problem of synthesis of cinnamyl alcohol dehydrogenase, and has greatly reduced the manufacturing cost of CAD. This exciting news comes from Hubei Yuancheng Pharmaceutical Co., Ltd. It is reported that the performance of CAD synthesized by this technology is exactly the same as that of CAD cloned by biotechnology, bringing unprecedented profit space to the synthesis of downstream products such as lignin.
Of course, in this process, there is no doubt about the role of cinnamyl alcohol, which is the basis of CAD synthesis. The quality of cinnamyl alcohol directly affects the synthesis quality of CAD and its application in performance.





Industry News

Related information—


Warmly congratulate our company on winning two national patents

Recently, the invention patents "a reaction kettle for the oxidation of cinnamaldehyde to prepare cinnamic acid" and "a potassium cinnamate drying device" applied by the company won the patent rights granted by the State Intellectual Property Office, and both obtained the Utility Model Patent Certificate. As an enterprise specializing in the production of cinnamon series products, we adhere to the management concept of "quality first, reputation first, management first, and service first", and pay special attention to the innovation of production technology while ensuring the production of high-quality products. Yu Chunping, General Manager, and Xu Qinfeng, Deputy General Manager, combined with the actual situation of the company's production line, collected the opinions of technical workers, studied, verified and tested in various ways, and devoted themselves to the patent research and development work, and finally achieved gratifying results. The acquisition of patents not only shows the technical strength of Nenmech and strengthens the core competitiveness of the company, but also brings efficient and high-quality services to customers through technological innovation. "Inheritance, innovation, diligence and development" is the corporate spirit of Nenmech. The company will continue to introduce high-quality talent teams to provide fundamental guarantee for independent innovation; Continue to increase investment in scientific research and enrich the enterprise's innovation and development potential; Further strengthen the interaction between schools and enterprises, enrich the company's technological innovation ability and the transformation ability of scientific and technological achievements, and provide strong technical support for the sustainable, healthy and rapid development of enterprises.