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Technical reform of cinnamyl alcohol dehydrogenase

Views:0     Author:Site Editor     Publish Time: 2021-11-09      Origin:Site

Cinnamyl alcohol dehydrogenase, as the key enzyme of plant secondary metabolism, especially lignin synthesis, is closely related to plant growth and development and resistance to pathogen invasion.

Lignin is one of the components of plant cell wall, which can connect cells. It can strengthen cell wall and bond fibers in plant tissues.

Its composition and properties are complex and have strong activity.

Substances with high relative molecular weight that are difficult to hydrolyze under the action of acid mainly exist in the cells of lignified plants and strengthen plant tissues.

Moreover, lignin also has many effects, such as antitumor effect, liver protection and antioxidant effect, antiviral effect, antispasmodic effect of smooth muscle, inhibitory activity of camp phosphodiesterase, immune enhancement, promoting the synthesis of protein and glycogen and so on.

As a key enzyme in lignin synthesis, a gene of cinnamyl alcohol dehydrogenase gene family is isolated from Xiaoshun bamboo shoots by RT-PCR and race, and cinnamyl alcohol dehydrogenase is produced by cloning technology, but the cost is so high that the price of downstream products also rises, which brings great difficulties to the application of products.

However, the latest research shows that this method can effectively synthesize cinnamyl alcohol dehydrogenase by using dehydrogenase to catalyze the reduction of cinnamyl alcohol and its derivatives in NADPH.

This research achievement is a major breakthrough in solving the synthesis problem of cinnamyl alcohol dehydrogenase, and greatly reduces the manufacturing cost of cinnamyl alcohol dehydrogenase.

This exciting news comes from Hubei Yuancheng Pharmaceutical Co., Ltd.

It is reported that the cinnamyl alcohol dehydrogenase synthesized by this technology has the same performance as the cinnamyl alcohol dehydrogenase cloned by biotechnology, which has brought unprecedented profit space to the synthesis of downstream products such as lignin.

Of course, in this process, there is no doubt about the role of cinnamyl alcohol. It is the basis of synthetic cinnamyl alcohol dehydrogenase.

The quality of cinnamyl alcohol directly affects the synthetic quality and performance application of cinnamyl alcohol dehydrogenase.


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